| Soccer (Japan) | |
| Solomon no Kagi (Japan) (Disk Writer) | |
| Souseiki Fammy - ROM-QD for 256K+64K (Japan) (Unl) | |
| Suishou no Dragon (Japan) | |
| Super Boy Allan (Japan) | |
| Super Lode Runner (Japan) | |
| Super Lode Runner II (Japan) (Disk Writer) | |
| Super Mario Bros. (Japan) | |
| Super Mario Bros. 2 (Japan) (En) | |
| Super Mario Bros. 2 (Japan) (En) (DV 2) | |
| Super Mario Bros. 2 (Japan) (En) (Game & Watch - Super Mario Bros.) | |
| Super Mario Bros. 2 (World) (GameCube, Wii and Wii U Virtual Console) | |
| Super Yume Kojo (Japan) (Pirate) | |
| Tama & Friends - Sanchoume Daibouken (Japan) | |
| Tanigawa Kouji no Shougi Shinan II - Meijin e no Michi - Shinban Tsumeshougi - Tsugi no Itte (Japan) (Disk Writer) | |
| Tanigawa Kouji no Shougi Shinan II - Meijin e no Michi (Japan) | |
| Tanigawa Kouji no Shougi Shinan II - Meijin e no Michi (Japan) (Beta) (1987-11-13) | |
| Tantei Jinguuji Saburou - Kiken na Futari - Kouhen (Japan) | |
| Tantei Jinguuji Saburou - Kiken na Futari - Kouhen (Japan) (Virtual Console) | |
| Tantei Jinguuji Saburou - Kiken na Futari - Zenpen (Japan) | |
| Tantei Jinguuji Saburou - Kiken na Futari - Zenpen (Japan) (Virtual Console) | |
| Tantei Jinguuji Saburou - Shinjuku Chuuou Kouen Satsujin Jiken (Japan) | |
| Tantei Jinguuji Saburou - Shinjuku Chuuou Kouen Satsujin Jiken (Japan) (Rev 1) (Disk Writer) | |
| Tantei Jinguuji Saburou - Shinjuku Chuuou Kouen Satsujin Jiken (Japan) (Rev 1) (Virtual Console) | |
| Tarot Uranai (Japan) | |
| Tennis (Japan) | |
| Tenshitachi no Houkago (Japan) (Unl) | |
| Time Twist - Rekishi no Katasumi de... - Kouhen (Japan) | |
| Time Twist - Rekishi no Katasumi de... - Zenpen (Japan) | |
| Titanic Mystery - Ao no Senritsu (Japan) | |
| Tobidase Daisakusen (Japan) (Famicom 3D System) | |
| Tonkachi Editor (Japan) (Unl) | |
| Tooyama no Kinsan Space Chou - Mr. Gold (Japan) | |
| Topple Zip (Japan) | |
| Topple Zip (Japan) (Project EGG) | |
| Transformers - The Headmasters (Japan) | |
| TwinBee (Japan) (Disk Writer) | |
| Ultraman - Kaijuu Teikoku no Gyakushuu (Japan) | |
| Ultraman - Kaijuu Teikoku no Gyakushuu (Japan) (Disk Writer) | |
| Ultraman 2 - Shutsugeki Katokutai (Japan) | |
| Ultraman Club - Chikyuu Dakkan Sakusen (Japan) | |
| Ultraman Club - Chikyuu Dakkan Sakusen (Japan) (Rev 1) | |
| Volleyball (Japan) | |
| Vs. Excitebike (Japan, USA) (En) (Virtual Console) | |
| Vs. Excitebike (Japan) (En) | |
| Wakusei Aton Gaiden (Japan) (National Tax Agency Demo) | |
| Wardner no Mori (Japan) | |
| Winter Games (Japan) | |
| Wrecking Crew (Japan) (Disk Writer) | |
| Xevious (Japan) (Disk Writer) | |