| Internado, El - Laguna Negra (Europe) (En,Fr,De,Es,It) | |
| International Athletics (Europe) (En,Fr,De,Es,It) | |
| Intervilles - Fais Gagner Ta Ville! - Le Jeu Officiel (France) | |
| Inu Gaisha (Japan) | |
| Inugamike no Ichizoku (Japan) | |
| InuYasha - Secret of the Divine Jewel (USA) | |
| Ippan Zaidan Houjin Nihon Kanji Shuujukudo Kentei Kikou Kounin - Kanjukuken DS (Japan) | |
| Iron Chef America - Supreme Cuisine (USA) | |
| Iron Feather (Japan) | |
| Iron Man (Europe) (En,Fr,De,Es,It) | |
| Iron Man (USA) (En,Fr,Es) | |
| Iron Man 2 - The Video Game (Europe) (En,Fr,De,Es,It) | |
| Iron Man 2 (USA) (En,Fr,Es) | |
| Iron Master - The Legendary Blacksmith (Japan) | |
| Iron Master - Wanggugui Yusangwa Segaeui Yeolsoe (Korea) | |
| Irozuki Tingle no Koi no Balloon Trip (Japan) | |
| Isanghan Naraui Princess (Korea) | |
| Ishin no Arashi - Shippuu Ryouma Den (Japan) | |
| Isola dei Famosi, L' (Italy) | |
| It's Tehodoki! Hannya Shingyou Nyuumon (Japan) | |
| Item Getter - Bokura no Kagaku to Mahou no Kankei (Japan) | |
| Itouke no Urawaza DS (Japan) | |
| Itsudemo Dokodemo - Onita Atsushi no Seiji Quiz DS (Japan) | |
| Itsudemo Dokodemo Dekiru Igo - AI Igo DS (Japan) | |
| Itsudemo Dokodemo Dekiru Shougi - AI Shougi DS (Japan) | |
| Itsumo no Shokuzai de Dekichau Suteki na Sweets to Gochisou. (Japan) | |
| Itsuwari no Rondo (Japan) | |
| Ivy the Kiwi - Tsuta ga Michibiku Monogatari. (Japan) | |
| Ivy the Kiwi (Europe) (En,Fr,De,Es,It) | |
| Ivy the Kiwi (USA) (En,Fr,Es) | |
| Izuna - Legend of the Unemployed Ninja (USA) | |
| Izuna - The Legend of the Ninja (Europe) (En,Fr,It) | |
| Izuna 2 - The Unemployed Ninja Returns (USA) | |