| E.T. The Extra-Terrestrial (E)(Blizzard) | |
| E.T. The Extra-Terrestrial (U)(Mode7) | |
| Earthworm Jim (U)(Mode7) | |
| Earthworm Jim 2 (E)(Patience) | |
| Earthworm Jim 2 (U)(Mode7) | |
| Ecks vs. Sever (E)(Independent) | |
| Ecks vs. Sever (U)(Mode7) | |
| Ed Edd n Eddy - The Mis-Edventures (E)(Independent) | |
| Ed, Edd n Eddy - Jawbreakers! (E)(Independent) | |
| Ed, Edd n Eddy - Jawbreakers! (U)(Eurasia) | |
| Ed, Edd n Eddy - Jawbreakers! (U)(Sir VG) | |
| Ed, Edd n Eddy - The Mis-Edventures (U)(Trashman) | |
| Egg Mania (U)(Mode7) | |
| EggMania Tsukande! Mawashite! Dossun Puzzle (J)(Evasion) | |
| Eggo Mania (E)(RDG) | |
| Eigo Kobuhen Eijukugo Hen 650 Phrases Blue Edition (J)(Mugs) | |
| Eigo Kubunhen (J)(Independent) | |
| Eitangohen - 2000 Words (J)(Mugs) | |
| Elemix (J)(Polla) | |
| Elevator Action - Old & New (J)(Eurasia) | |
| Elf - The Movie (U)(Venom) | |
| Elf Bowling 1 & 2 (U)(Trashman) | |
| Elf The Movie (E)(Independent) | |
| Emerald Cross v2.1 | |
| Emerald Cro | |
| ss v3.5 | |
| Emerald the Hedgehog12345! in sonic battle | |
| Emerald Trashlocke Edition | |
| Emerald Uncensored Beta 2 | |
| Enchanted - Once Upon Andalasia (U)(Sir VG) | |
| Eragon (E)(Rising Sun) | |
| Eragon (U)(Rising Sun) | |
| Erementar Gerad (J)(Supplex) | |
| ESPN Final Round Golf (E)(Paracox) | |
| ESPN Final Round Golf 2002 (U)(Mode7) | |
| ESPN Great Outdoor Games - Bass 2002 (U)(Mode7) | |
| ESPN Great Outdoor Games - Bass Tournament (E)(Lightforce) | |
| ESPN International - Winter Sports (E)(TrashMan) | |
| ESPN International - Winter Sports 2002 (U)(Mode7) | |
| ESPN Winter X-Games - Snowboarding 2 (E)(Independent) | |
| ESPN Winter X-Games - Snowboarding 2002 (J)(Eurasia) | |
| ESPN Winter X-Games - Snowboarding 2002 (U)(Mode7) | |
| ESPN X-Games - Skateboarding (E)(Patience) | |
| ESPN X-Games - Skateboarding (J)(Nil) | |
| ESPN X-Games - Skateboarding (U)(Mode7) | |
| Estopolis Densetsu (J)(Eurasia) | |
| European Super League (E)(Fett1) | |
| Evergirl (U)(Trashman) | |
| EX Monopoly (J)(Eurasia) | |
| Exciting Bass (J)(GBATemp) | |
| Expedition Der Stachelbeeren Zoff Im Zoo (G)(Rising Sun) | |